Primary Identifier | MGI:2445836 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CNTN2-CNTN1)1Gnn |
Strain of Origin | (CBA x C57BL/10)F1 | Is Recombinase | false |
Is Wild Type | false |
description | Five transgenic founders were created. Representative results were obtained from line TAG/F3. |
molecularNote | The transgene consists of the human CNTN2 proximal promoter and a full-length CNTN1 cDNA sequence. The CNTN2 portion includes exons 1-2. The promoter sequences were used to drive transgene expression the brain. Immunohistochemical analysis of postnatal day 4 animals showed transgene expression throughout most of the external granular layer (EGL). Expression of the transgene was confirmed by RT-PCR. |