Primary Identifier | MGI:2446075 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Cga-LHB/CGB)94Jhn |
Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains the entire bovine luteinizing hormone beta (LHB) cDNA fused to 87 bp encoding the c-terminal peptide (CTP) of the human chorionic gonadotropin beta subunit (CGB). The bovine glycoprotein hormone alpha subunit (CGA) promoter (positions -315 to +45) was used to drive expression in gonadotropes. Immunohistochemical analysis confirmed both LHB and CTP expression in the pituitaries. |