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Allele : Ltb/Tnf<tm1Dvk> tumor necrosis factor; targeted mutation 1, Dmitry V Kuprash

Primary Identifier  MGI:2446563 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tnf
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 5.3 kb region, containing exon 3 of the Ltb locus and exons 3 and 4 of the Tnf locus, was left floxed after the integration of a targeting vector containing a loxP-neo cassette in intron 2 of the Ltb locus and two downstream loxP sites the intergenic region between Ltb and Tnf and in intron 2 of the Tnf locus. An additional loxP site located within the Lta locus in the targeting vector was not integrated due to partial homologous recombination.
  • mutations:
  • Insertion
  • synonyms:
  • (LTBeta/TNF)<T>,
  • (LTBeta/TNF)<T>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele