Primary Identifier | MGI:2446563 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Tnf |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 5.3 kb region, containing exon 3 of the Ltb locus and exons 3 and 4 of the Tnf locus, was left floxed after the integration of a targeting vector containing a loxP-neo cassette in intron 2 of the Ltb locus and two downstream loxP sites the intergenic region between Ltb and Tnf and in intron 2 of the Tnf locus. An additional loxP site located within the Lta locus in the targeting vector was not integrated due to partial homologous recombination. |