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Allele : Tg(IT2)4Kka transgene insertion 4, Kirsi Kananen
Primary Identifier  MGI:2446096 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(IT2)4Kka
Strain of Origin  (C57BL/6J x DBA/2J)F2 Is Recombinase  false
Is Wild Type  false
description  The transgene contains the mouse inhibin alpha promoter and the wild-type alleles of the SV40 Tag and tag (large and small T antigen) genes. The "IT2" construct carried a 2-kb fragment of the mouse inhibin alpha promoter.
    RT-PCR analysis detected expression of the SV40 transgene in testis. This line did not develop gonadal tumors. ...
molecularNote  2.7 kb of SV40 sequences, including the large T and small t antigen coding regions and polyadenylation signal, were fused to a small mouse Inha promoter fragment and used for the transgene. Transgene expression was confirmed by RT-PCR analysis.
  • mutations:
  • Insertion
  • synonyms:
  • IT2,
  • IT2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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