| Primary Identifier | MGI:2446351 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Prrx1-Hand2/VP16)1Eno |
| Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene consists of a mouse Prrx1 promoter and a Hand2 cDNA fused to the viral coactivator VP16 at the C-terminus. The mouse Prrx1 promoter was used to drive transgene expression in the forelimb bud and anterior mesoderm of the hindlimb in E10.5 embryos. The Hand2 construct also contains an N-terminal Myc epitope tag and a 3' human growth hormone polyadenylation signal. |
