| Primary Identifier | MGI:2446491 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hcst |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This allele is derived from Hcsttm1Cln by mating mutant animals to cre deleter strain TgN(CMV-cre)1Cgn. Resulting progeny are deleted for the floxed neo cassette and contain a single loxP site in place of exon 1 and intron 1. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis of lysates from NK cells and CD8+ cells. |