| Primary Identifier | MGI:2446659 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Prnp)37Jcol |
| Strain of Origin | mixed | Is Recombinase | false |
| Is Wild Type | false |
| description | The founder line contained between 5 and 7 copies of the transgenic construct. Eggs of mixed background involve: 129/Sv * C57BL * FVB/N. |
| molecularNote | A transgenic construct was generated by inserting the Prnp open reading frame flanked by loxP sites into a cosmid vector. The regulatory sequences contained within cosmid CosSHaTet drove expression in the brain. Western blot analysis of of the founder line showed overexpression of Prp in brain tissue. |
