Primary Identifier | MGI:2447439 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Mt1-GHRH)1Lstu |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene consists of a 220 bp fragment of the human GHRH gene encoding the N-terminal 31 amino acid signal peptide and a 40 amino acid form of the protein fused to a mouse Mt1 promoter. Overexpression of the human GHRH transgene was observed by in situ hybridization analysis of pituitary tumors from transgenic animals over 10 months of age. |