Primary Identifier | MGI:2447595 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TF-APOE)1Viz |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 4.9 kb genomic fragment containing exons 1 through 4 of the human APOE gene was adjoined to a 690 bp fragment of the human transferrin (TF) gene. RNase protection and Western blot analysis detected epsilon 2 (APOE2) transcript and protein in brain and liver tissues obtained from transgenic mice. Immunohistochemical analysis indicated expression in glial cells |