Primary Identifier | MGI:2447624 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Dlx5 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Coding regions of both Dlx5 and Dlx6 were deleted and replaced with lacZ-floxed-RSV-neo construct via a single homologous recombination event. The gene targeting event also generated a transcriptionally silent genomic duplication spanning both Dlx5 and Dxl6. Absence of gene expression was confirmed by RT-PCR and whole mount in situ hybridization. |