| First Author | Nikolajsen GN | Year | 2015 |
| Journal | Neurobiol Aging | Volume | 36 |
| Issue | 11 | Pages | 2954-2962 |
| PubMed ID | 26364735 | Mgi Jnum | J:232245 |
| Mgi Id | MGI:5776402 | Doi | 10.1016/j.neurobiolaging.2015.08.004 |
| Citation | Nikolajsen GN, et al. (2015) Quantitative analysis of the capillary network of aged APPswe/PS1dE9 transgenic mice. Neurobiol Aging 36(11):2954-2962 |
| abstractText | A combination of immunohistochemical and stereological techniques were used to investigate the capillary network in the cerebral cortex of 18-month-old APPswe/PS1dE9 transgenic (Tg) mice and control littermates. Data regarding total capillary length, segment number, diffusion radius, and pericyte number are presented. The total length was 60 meters and there was a one-to-one relationship between the number of capillary segments and pericytes in both groups. Significant differences were not observed in the Tg and wild-type controls indicating that the Alzheimer's-like amyloidosis produced in this Tg mouse has a minimal affect on the structural integrity of the cerebral capillary network. |
