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Allele : Tg(Col2a1-Runx2)2Tok transgene insertion 2, Toshihisa Komori

Primary Identifier  MGI:2447358 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Col2a1-Runx2)2Tok
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The entire coding region of mouse Runx2 (with translation starting from exon 1) was cloned between the promoter and enhancer elements of Col2a1, which were used to drive transgene expression in chondrocytes. Transgene expression was confirmed by Northern blot analysis of RNA extracted from the head or trunk of day E12.5 transgenic embryos. Both type I and type II isoforms are expressed from this transgene.
  • mutations:
  • Insertion
  • synonyms:
  • Col2a1-type II Cbfa1,
  • Col2a1-type II Cbfa1
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele