| Primary Identifier | MGI:2447359 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Col2a1-Runx2*)3Tok |
| Strain of Origin | (C57BL/6 x C3H)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A cDNA fragment encoding the runt domain of mouse Runx2 was cloned between the promoter and enhancer elements of Col2a1 (active in chondrocytes) to produce a dominant negative transgene. Transgene expression was confirmed by Northern blot analysis of RNA extracted from the head or trunk of day E12.5 transgenic embryos. |
