| Primary Identifier | MGI:2447492 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Gfap-Il12b)GFp40Ilc |
| Strain of Origin | (C57BL/6J x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | One transgenic animals carrying only the Tg(Gfap-IL12b)2Ilc transgene was created and used to establish a transgenic line. This line is referred to as the GF-p40 line. |
| molecularNote | The transgene consists of a mouse IL12b sequence (nucleotides 1-1055) under the control of a mouse Gfap promoter. The mouse Gfap promoter was used to drive transgene expression in astrocytes. A human growth hormone polyadenylation sequence and SV40 splice donor/acceptor site were also included in the construct. |
