| Primary Identifier | MGI:2447829 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Stat2 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exons 1-4 with a PGK-neo cassette via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of primary mouse embryonic fibroblast (PMEF) extracts prepared from homozygous mutant embryos. Stat1 expression was reduced by 50% in Stat2-deficient cells. |
