| Primary Identifier | MGI:2447847 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(RHO-SCA7)R7NJman |
| Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
| Is Wild Type | false |
| description | Transgenic lines A, B, and C were constructed. Line C carries 50-100 copies of the integrated transgene and expresses the highest amount of transgene product. |
| molecularNote | The transgene consists of a human rhodopsin promoter (containing the RER enhancer element), the full-length wild-type human Sca7 gene carrying 10 glutamine repeat units, and an SV40 intron and polyadenylation sequence. Transgene expression was observed in rod cells by immunofluorescence, and in retinal extracts by Western blot. |
