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Allele : Tg(tetO-Utrn)1Ked transgene insertion 1, Kay E Davies

Primary Identifier  MGI:2448084 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-Utrn)1Ked
Strain of Origin  Not Specified Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  A full-length cDNA encoding mouse utrophin with an N-terminal FLAG epitope tag was inserted between the cytomegalovirus (CMV) minimal promoter and polyadenylation signal, all downstream of the tetracycline operator (tetracycline responsive element). Tissue-specific tetracycline transactivator (tTA) or reverse transactivator (rtTA) expression from a second transgene permits regulation of utrophin expression by administration of doxycycline in drinking water.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(UTR-TET)Ked,
  • Utr-TET,
  • Tg(UTR-TET)Ked,
  • Utr-TET
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele