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Allele : Ods<Tg(Dct-Tyr)1220Ove> ocular degeneration with sex reversal; transgene insertion 1220, Paul Overbeek

Primary Identifier  MGI:2447988 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Ods
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
description  This mutation is proposed to delete a long-range regulatory element that mediates expression of Sox9 in a gender specific manner.
molecularNote  Two copies of a transgene inserted randomly 1 Mb upstream of the Sox9 gene, and also caused a deletion of 150 kb at the insertion site. The transgene consisted of Dct promoter sequence driving expression of a tyrosinase minigene.
  • mutations:
  • Deletion,
  • Insertion
  • synonyms:
  • Ods,
  • Ods,
  • Ods<Tg(Tyr)1220Ove>,
  • Ods<Tg(Tyr)1220Ove>,
  • OVE1220,
  • OVE1220
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1 Feature

Trail: Allele

Genome

0 Expresses

1 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele