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Publication : Linkage mapping of the mouse nephrosis (nep) gene to chromosome 15.

First Author  Okamoto M Year  2001
Journal  J Vet Med Sci Volume  63
Issue  12 Pages  1347-50
PubMed ID  11789617 Mgi Jnum  J:74275
Mgi Id  MGI:2158012 Doi  10.1292/jvms.63.1347
Citation  Okamoto M, et al. (2001) Linkage mapping of the mouse nephrosis (nep) gene to chromosome 15. J Vet Med Sci 63(12):1347-50
abstractText  ICGN is a partially inbred strain of mice with nephrotic syndrome caused by spontaneous glomerular lesion. It has been reported that the albuminuria in ICGN mouse was controlled by at least a single autosomal recessive gene (nep). In this study, we mapped the nep locus by linkage analysis of backcross progeny between ICGN and MSM mice using DNA pooling method. The linkage analysis revealed that the nep locus was localized on the distal part of chromosome 15.
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