| First Author | Rogers DC | Year | 2001 |
| Journal | Neurosci Lett | Volume | 306 |
| Issue | 1-2 | Pages | 89-92 |
| PubMed ID | 11403965 | Mgi Jnum | J:76724 |
| Mgi Id | MGI:2180137 | Doi | 10.1016/s0304-3940(01)01885-7 |
| Citation | Rogers DC, et al. (2001) SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. Neurosci Lett 306(1-2):89-92 |
| abstractText | Mouse models of neurological abnormalities are only valuable if accurately assessed. The three-stage SHIRPA procedure is used for the standardised assessment of mouse phenotype and has been reported in a high throughput experiment in which different mutants were ascertained at one age point using stage 1 of the protocol. In this study we have validated SHIRPA using a large cohort with one single mutation, 'legs at odd angles that causes neurological dysfunction. The cohort aged from 1 to 16 months during this study and this is the first longitudinal SHIRPA analysis. |
