Primary Identifier | MGI:2448658 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(APOA1-CETP)1Dsg |
Strain of Origin | (C57BL/6J x SJL)F2 | Is Recombinase | false |
Is Wild Type | false |
description | Two transgenic lines were created. Line CETP4 exhibits 3-fold enzyme activity and was used in most studies. |
molecularNote | The transgene consists of a human APOA1 promoter and a 1.5 kb human CETP cDNA sequence. Northern blot analysis showed that transgene expression is exclusive to the liver. |