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Allele : Prkaa2<tm1.1Vio> protein kinase, AMP-activated, alpha 2 catalytic subunit; targeted mutation 1.1, Benoit Viollet
Primary Identifier  MGI:2448467 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prkaa2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
description  ES cell line = MPI-I (MPI1).
molecularNote  The floxed region containing the exon encoding amino acids 189 through 260 and a downstream neo cassette was excised from Prkaa2tm1Vio in the germline via in vivo cre-mediated recombination. Protein was undetected by Western blot analysis of liver and muscle tissue obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • AMPKalpha2<->,
  • Ampka2<->,
  • AMPK<->,
  • alpha2 AMPK KO,
  • AMPKalpha2<->,
  • alpha2 AMPK KO,
  • Ampka2<->,
  • AMPK<->,
  • alpha2KO,
  • alpha2KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

115 Publication categories

Trail: Allele




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