Primary Identifier | MGI:2448699 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Edn1-NOS3)22Yky |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
description | Four transgenic lines (22, 65, 88, and 105) were established. |
molecularNote | The transgene consists of a mouse Edn1 promoter, active in the vascular wall, and a bovine NOS3 cDNA. RNase protection assay detected transgene expression in heart, lung, aorta, and uterus. Low levels of transgene expression was also observed in brain, liver, kidney, and intestine. |