| Primary Identifier | MGI:2448988 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Nkx2-5 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequence encoding enhanced GFP was inserted at codon 35 of the endogenous locus via homologous recombination. In addition to the insertion, sequence encoding amino acids 141 through 184 containing the N-terminal part of the homeodomain was deleted, introducing a frameshift mutation. Expression of GFP was similar to that of the endogenous gene. |
