| Primary Identifier | MGI:2450289 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Wnt3 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| description | Oppositely-oriented loxP sites in Wnt3tm2Brd and Trp53tm2Brd, which was generated on the same Chr 11 homolog (in cis) in ES cells already carrying the Wnt3 mutation, served as the proximal and distal breakpoints, respectively, of a 24-cM engineered inversion, In(11Trp53;11Wnt3)8Brd. (J:56548) |
| molecularNote | A 2.1-kb genomic DNA fragment containing exon 3 and most of exon 4 were replaced with a cassette, oriented toward the centromere, containing a neomycin resistance gene, a loxP site, the 5' half of an Hprt minigene, and a Krt14-Agouti coat color transgene. |
