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Allele : Tll1<tm1Dgr> tolloid-like; targeted mutation 1, Daniel S Greenspan

Primary Identifier  MGI:2449853 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tll1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of exon 6, which encodes the zinc-binding active site, with a neomycin resistance gene resulting in a frameshift mutation and premature stop codon. RT-PCR analysis of RNA from whole homozygous mutant embryos at day E13.5 confirmed the absence of gene expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Tll1<-/->,
  • Tll1<-/->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele