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Allele : Pax6<tm1Lan> paired box 6; targeted mutation 1, Richard A Lang
Primary Identifier  MGI:2449854 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Pax6
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The 341 bp ectoderm enhancer was deleted and replaced with a floxed neo cassette via homologous recombination. Transient expression of cre recombinase in correctly targeted cells removed the floxed neo cassette leaving behind a single loxP site in place of the ectoderm enhancer. PCR genotype analysis confirmed the mutant allele in homozygous animals.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Pax6<deltaEE>,
  • Pax6<deltaEE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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