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Allele : Gzma<tm1Simn> granzyme A; targeted mutation 1, Markus M Simon

Primary Identifier  MGI:2449926 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gzma
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by insertion of a neomycin resistance cassette into exon 4 by homologous recombination. Western blot analysis confirmed the absence of protein product and cytochemical analysis demonstrated the absence of enzyme activity in cytotoxic T cells in homozygous mutant animals.
  • mutations:
  • Insertion
  • synonyms:
  • gzm A-,
  • gzmA-,
  • GrzA-,
  • gzmA-,
  • gzm A-,
  • GrzA-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

56 Publication categories

Trail: Allele