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Allele : Unc13a<tm1Bros> unc-13 homolog A; targeted mutation 1, Nils Brose

Primary Identifier  MGI:2449468 Allele Type  Targeted
Attribute String  Null/knockout Gene  Unc13a
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by the replacement of 4 exons encoding amino acids 494-619 (which includes the C1 domain) with a neomycin resistance cassette via homologous recombination. The null allele was confirmed by Western blot analysis using antibodies directed against the extreme N- and C-termini of the protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Munc13-1-deficient,
  • Munc13-1-deficient,
  • Unc13a<KO>,
  • Unc13a<KO>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

38 Publication categories

Trail: Allele