Primary Identifier | MGI:2449468 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Unc13a |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by the replacement of 4 exons encoding amino acids 494-619 (which includes the C1 domain) with a neomycin resistance cassette via homologous recombination. The null allele was confirmed by Western blot analysis using antibodies directed against the extreme N- and C-termini of the protein. |