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Allele : Gabrb3<tm1Uru> GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3; targeted mutation 1, Uwe Rudolph
Primary Identifier  MGI:2449764 Allele Type  Targeted
Attribute String  Not Specified Gene  Gabrb3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An asparagine to methionine substitution within the second transmembrane domain was achieved by the introduction of 2 nucleotide substitutions (AAC to ATG) in exon 8 at codon 265 (N265M). A single loxP site remained downstream of exon 8 after a floxed neo cassette was excised via in vivo cre mediated recombination.
  • mutations:
  • Single point mutation,
  • Nucleotide substitutions
  • synonyms:
  • Beta3(N265M),
  • beta3N265M,
  • Beta3(N265M),
  • beta3N265M
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele




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