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Allele : Atp1a1<tm1Ling> ATPase, Na+/K+ transporting, alpha 1 polypeptide; targeted mutation 1, Jerry B Lingrel

Primary Identifier  MGI:2451290 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atp1a1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 15 through 18 were replaced with an hprt cassette via homologous recombination. Both alpha 1 transcript and protein levels were reduced by ~40% in heterozygous mutant hearts. An aberrant alpha 1 transcript was detected but was not expected to produce a functional protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • alpha1<->,
  • alpha1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

19 Publication categories

Trail: Allele