|  Help  |  About  |  Contact Us

Allele : Atp1a2<tm2Ling> ATPase, Na+/K+ transporting, alpha 2 polypeptide; targeted mutation 2, Jerry B Lingrel

Primary Identifier  MGI:2451291 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atp1a2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of an hprt cassette into exon 4 resulted in an alpha 2 isoform specific disruption. Both alpha 2 transcript and protein levels were reduced by ~50% in heterozygous mutant hearts. An aberrant alpha 2 transcript was detected but was not expected to produce a functional protein.
  • mutations:
  • Insertion
  • synonyms:
  • alpha2<->,
  • alpha2<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele