Primary Identifier | MGI:2450662 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ros1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced two exons that encode the protein kinase domain. This region corresponds to nucleotides 6267-6467 of the cDNA. Western blot analysis using antibodies against a carboxy-terminal peptide did not detect protein in epididymal extracts from homozygous mutant mice. |