First Author | Congleton YH | Year | 2006 |
Journal | Infect Immun | Volume | 74 |
Issue | 11 | Pages | 6501-4 |
PubMed ID | 16954401 | Mgi Jnum | J:113550 |
Mgi Id | MGI:3686946 | Doi | 10.1128/IAI.00597-06 |
Citation | Congleton YH, et al. (2006) Mice Naturally Resistant to Yersinia pestis {Delta}pgm Strains Commonly Used in Pathogenicity Studies. Infect Immun 74(11):6501-4 |
abstractText | We report that females of some substrains of inbred mouse strain 129 are resistant to systemic plague due to conditionally virulent Deltapgm strains of Yersinia pestis; however, fully virulent Y. pestis is not attenuated in these mice. Therefore, these mice offer a powerful system in which to map in parallel host resistance traits and opposing bacterial virulence properties for plague. |