| Primary Identifier | MGI:2451034 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mchr1 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exon 2 with a neomycin resistance cassette. The targeted mutation results in deletion of sequences spanning the first transmembrane domain to the stop codon. Absence of gene expression in homozygous mutant animals was confirmed by in situ hybridization analysis of coronal brain sections. |
