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Publication : A human CD2 minigene directs CRE-mediated recombination in T cells in vivo.

First Author  Wilson TJ Year  2002
Journal  Genesis Volume  33
Issue  4 Pages  181-4
PubMed ID  12203915 Mgi Jnum  J:81648
Mgi Id  MGI:2449757 Doi  10.1002/gene.10107
Citation  Wilson TJ, et al. (2002) A human CD2 minigene directs CRE-mediated recombination in T cells in vivo. Genesis 33(4):181-4
abstractText  We have produced a mouse line that expresses the Cre recombinase under the regulation of a human CD2 minigene to facilitate Cre-specific recombination in T lymphocytes. These mice express Cre in thymocytes and T cells and are capable of efficient site-specific recombination as shown in the spleen and thymus, but not other tissues. These mice thus provide an excellent resource for the study of gene function during thymocyte development and in mature T cells.
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