| First Author | Kelly MN | Year | 2005 |
| Journal | Infect Immun | Volume | 73 |
| Issue | 1 | Pages | 617-21 |
| PubMed ID | 15618203 | Mgi Jnum | J:94837 |
| Mgi Id | MGI:3521595 | Doi | 10.1128/IAI.73.1.617-621.2005 |
| Citation | Kelly MN, et al. (2005) Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun 73(1):617-21 |
| abstractText | We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R(-/-) mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear leukocytes to infected sites during early infection. |
