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Allele : Lpl<tm1Bres> lipoprotein lipase; targeted mutation 1, Jan L Breslow

Primary Identifier  MGI:2651805 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lpl
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encompassing a portion of exon 1, including the start codon and signal sequence, and all of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Lipoprotein lipase activity was shown to be almost completely ablated in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • L1,
  • LPL<->,
  • LPL<->,
  • L1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

30 Publication categories

Trail: Allele