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Publication : The cortical vibrissae representation is normal in transgenic mice lacking the 5-HT(1B) receptor.

First Author  Boylan CB Year  2000
Journal  Brain Res Dev Brain Res Volume  120
Issue  1 Pages  91-3
PubMed ID  10727735 Mgi Jnum  J:109182
Mgi Id  MGI:3626046 Doi  10.1016/s0165-3806(99)00194-7
Citation  Boylan CB, et al. (2000) The cortical vibrissae representation is normal in transgenic mice lacking the 5-HT(1B) receptor. Brain Res Dev Brain Res 120(1):91-3
abstractText  Recent studies have suggested that 5-HT may modulate thalamocortical development in somatosensory cortex (S-I) of rats and mice, and that the 5-HT(1B) receptor may play a critical role in this process. Analysis of CO-stained sections through lamina IV of S-I in perinatal and adult 5-HT(1B) knockout mice revealed a normal vibrissae-related pattern, indicating that activation of the 5-HT(1B) receptor is not necessary for the normal development of the vibrissae representation in S-I.
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