First Author | Boylan CB | Year | 2000 |
Journal | Brain Res Dev Brain Res | Volume | 120 |
Issue | 1 | Pages | 91-3 |
PubMed ID | 10727735 | Mgi Jnum | J:109182 |
Mgi Id | MGI:3626046 | Doi | 10.1016/s0165-3806(99)00194-7 |
Citation | Boylan CB, et al. (2000) The cortical vibrissae representation is normal in transgenic mice lacking the 5-HT(1B) receptor. Brain Res Dev Brain Res 120(1):91-3 |
abstractText | Recent studies have suggested that 5-HT may modulate thalamocortical development in somatosensory cortex (S-I) of rats and mice, and that the 5-HT(1B) receptor may play a critical role in this process. Analysis of CO-stained sections through lamina IV of S-I in perinatal and adult 5-HT(1B) knockout mice revealed a normal vibrissae-related pattern, indicating that activation of the 5-HT(1B) receptor is not necessary for the normal development of the vibrissae representation in S-I. |