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Allele : Areg<Mcub> amphiregulin; modifier of curly bare

Primary Identifier  MGI:2653137 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Areg
Inheritance Mode  Dominant Strain of Origin  V/LeJ
Is Recombinase  false Is Wild Type  false
molecularNote  A T to G mutation occured in the G-GT splice donor site of exon 1 disrupting the donor site and resulting in the use of an alternative downstream splice site. The alternative splice site adds 22 nucleotides to the sequence resulting in a frame-shift and introducing a premature stop codon. Mcub is dominant modifier allele that causes a wavy coat in mice homozygous for the cub mutation.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele