Primary Identifier | MGI:2655195 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Six1 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
description | These ES cells were additionally targeted in J:98519 to create Six1Six4 double knockouts. |
molecularNote | The N-terminal portion of the gene was deleted by replacement of exon 1 with a lacZ-PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by immunohistochemical analysis. |