| Primary Identifier | MGI:2655703 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Hbegf |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The loxP-flanked, wild-type Hbegf cDNA was excised from Hbegftm1Mek via Cre-mediated recombination in progeny of a cross between mice with the floxed allele and mice bearing a ubiquitously expressed cre transgene. The bacterial beta-galactosidase gene (lacZ) and the Pgk-neo cassette remain in place of most of exon 1 through exon 3 and most of the third intron of the native gene. Expression of lacZ is driven by the endogenous promoter; the beta-galactosidase protein is localized to the nucleus. |
