| Primary Identifier | MGI:2657240 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nos3 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. The gene targeting event results in deletion of the first 54 amino acids and a frameshift of the remaining sequence. Absence of gene expression in homozygous mutant animals was confirmed by immunohistochemistry. |
