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Allele : Mpl<tm1Wsa> myeloproliferative leukemia virus oncogene; targeted mutation 1, Warren S Alexander

Primary Identifier  MGI:2660811 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mpl
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced the first 5 coding exons and sequences containing the initiation codon and the transcription start site. Radioimmunoassays demonstrated that no functional protein was expressed on the cell surface of bone marrow or spleen cells derived from homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • mpl -,
  • mpl -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

48 Publication categories

Trail: Allele