Primary Identifier | MGI:2664161 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Rho-GUCA1B)1Jnc |
Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 0.7 kb cDNA fragment encoding the bovine GUCA1B was adjoined to a 4.4 kb murine rhodopsin promoter and a polyadenylation signal from the murine Prm1 locus. Expression of the bovine GUCA1B was approximately 2-fold higher than that of the endogenous murine Guca1B. The pattern of retinal expression was shown to be similar to that of murine Guca1b by Indirect immunofluorescent labeling. |