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Allele : Cd2ap<tm1Shaw> CD2-associated protein; targeted mutation 1, Andrey S Shaw

Primary Identifier  MGI:2664945 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd2ap
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
description  Heterozygous mutant mice exhibit highly organized microtubular deposits in the mesangium which is characteristic in human immunotactoid glomerulopathy (J:84748).
molecularNote  The sequences encoding the first SRC homology 3 domain was replaced with a neomycin-resistance gene. Immunoblots of kidney, liver, spleen, and thymus proteins from homozygous mice indicated the absence of gene product.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Cd2ap-,
  • Cd2ap-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

40 Publication categories

Trail: Allele