| Primary Identifier | MGI:2668479 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Runx1 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 10kb segment including exons 7 and 8 (but not the splice acceptor site of exon 7) was replaced with lacZ coding sequence followed by a PGK-neomycin resistance gene. A fusion protein is produced which contains the N-terminal 242 amino acids of Runx1, including its nuclear localization sequences, combined with beta-galactosidase sequences. The fusion protein lacks Runx1 function. |
