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Allele : Pdgfb<tm3Cbet> platelet derived growth factor, B polypeptide; targeted mutation 3, Christer Betsholtz

Primary Identifier  MGI:2670572 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pdgfb
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon was inserted into exon 6 via homologous recombination of a targeting vector which also included a loxP flanked neo cassette in intron 5. The insertion of the stop codon precludes the translation of the retention moftif. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Pdgfbtm3.1Cbet.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele