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Allele : Runx1<tm1Buch> runt related transcription factor 1; targeted mutation 1, Frank Buchholz

Primary Identifier  MGI:2671464 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Runx1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted into intron 5, 1496 bp downstream of exon 5. This allele, in combination with allele Runx1t1tm1Buch in the same cells was used for the engineering of T(4;16), a reciporical translocation that replicates the human acute myeloid leukemia (AML) associated translocation, T(8;21).
  • mutations:
  • Other
  • synonyms:
  • AML<X>,
  • AML<X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele