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Allele : Cd3g<tm2Amk> CD3 antigen, gamma polypeptide; targeted mutation 2, Ada M Kruisbeek

Primary Identifier  MGI:2673301 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd3g
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3' portion of exon 5 and all of exon 6 were deleted by the incorporation of a targeting vector. The deleted region included sequence encoding the ITAM domain. While protein was undetected by immunoprecipitation, it was detected in homozygous mutant mice by SDS-PAGE, putatively because the anti-Cd3g serum recognizes epitopes present in the deleted region.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CD3gamma-deltaITAM,
  • CD3gamma-deltaITAM,
  • CD3gamma<deltaI>,
  • CD3gamma<deltaI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele